Lt. Wakes is a vengeful police detective determined to solve the murders of his partner and an informant, and joins forces with a witness injured during the shootings. After the killers pursue the witness across the abandoned floor of a hospital, she confirms Wakes's worst fears. Alone and trapped in a locked-down hospital, an injured young woman must escape a pair of vicious killers who are after the only piece of evidence that can implicate them in a grisly murder, the bullet in her leg.